Discover, Design, Develop.

Crystallize, Grow and Scale-up!

Designing robust, transportable and scalable crystallization processes that deliver quality bulk powder with specific physical properties

Quality, Quantity and Sustainability!

InCryst Ltd. is a Contract Research Organisation (CRO) offering solid form screening and crystallization process development services to the pharmaceutical, fine chemicals, cosmetics, veterinary, agro and food industries.

Crystallization is not just a niche technique; it stands as a linchpin process, central to nearly every small molecule synthesis in various industries. Whether in pharmaceuticals, where it ensures the purity and stability of life-saving medications, or in cosmetics, where it refines ingredients for consumer-friendly products, crystallization plays a pivotal role. In fine and bulk chemicals, it underpins the production of high-quality compounds essential across industries. Agriculture and the food sector rely on crystallization for refining ingredients, enhancing product quality, and extending shelf life. Even in veterinary medicine, crystallization is vital for formulating pharmaceuticals to safeguard animal health. Its universal significance and adaptability in diverse sectors underscore crystallization as an indispensable cornerstone of modern industrial processes.

While we don't aspire to become a large corporation, our vision aligns more with that of a small, dedicated, and sustainable business model. We draw inspiration from the timeless essence of a quality bakery in France, which has consistently delivered exceptional affordable products for generations. Similarly, we prioritize attention to detail, craftsmanship, and personalized service in our operations. By embracing this approach, we aim to establish ourselves as a trusted and long-standing partner, offering enduring value to our clients and contributing to the advancement of solid form screening and crystallization process development in the pharmaceutical and chemical industries.

Better, Faster, Cheaper!

We design and develop robust crystallization (batch and continuous) processes that deliver high quality (pure) crystals that enable the large-scale production of bulk powders with defined physical properties tailored for downstream processes and end users. Our approach is performed via a combined experimental and modelling workflow for early to late-stage candidates, applied to small and large molecules (peptide, pro-drug, drug linker, polymer), including systems that are prone to Liquid-Liquid Phase Separation (LLPS i.e. 'oiling out').

To draw an analogy with the restaurant industry, our aspiration is to offer the equivalent of a three-star Michelin meal in terms of quality, precision, and attention to detail at the pace and affordability equivalent of a fast-food restaurant, without compromising on the excellence and value we provide to our clients.

E pluribus unum...

At our solid form screening service, we understand the critical importance of finding the right crystalline phase during preclinical development. We utilize conventional and non-conventional methodologies to conduct comprehensive screening of potential solid forms, identifying the most thermodynamically stable form that produces ideal physico-chemical properties characterized by state-of-the-art technologies. By selecting the optimal solid form for your drug product, we can help you achieve intellectual property protection, consistent downstream production, and the desired clinical outcomes. Our thorough approach to solid form screening can help prevent unintended consequences during scale-up, processing, or storage, ensuring the safety and efficacy of your API.

you will own everything...

At InCryst, we believe in providing our clients with the best possible service, including the assurance that they will own the intellectual property (IP) for any solid form screening we conduct on their behalf. This means that our clients will have full ownership of any discoveries or inventions resulting from our screening services and can take steps to protect their IP through patents or other means. We understand the importance of protecting our clients' innovations and ensuring they have the freedom to operate in their respective fields.

Therefore, we are committed to providing transparent and reliable services that not only meet our clients' needs but also respect their intellectual property rights.

Discovery Park, Innovation House,
Sandwich CT13 9FF, Kent,
United Kingdom

+44 7946 022 451

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